Brief Information of the Compound and Protein
Compound Name
5-chloro-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1,2-dihydrospiro[indole-3,4'-piperidine]
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PubChem ID
CID: 11702853
SID: 16807500
Canonical SMILES
Clc1ccc2N(CC3(CCNCC3)c2c1)c1ncnc2[nH]ccc12
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Compound Formula C18H18ClN5
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
AGC protein kinase group
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AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.8 nM