Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)-boldine
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 PubChem ID
CID: 10154
SID: 16183941
Canonical SMILES
COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c-2c34)cc1O
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Compound Formula C19H21NO4
Compound Structure
Protein Name
 Protein Info 
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 81000 nM
   TI
   LI
   LO
   TS
2
Ki = 67000 nM
   TI
   LI
   LO
   TS