Brief Information of the Compound and Protein
Compound Name
(S)-3-bromo-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
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PubChem ID
CID: 10409038
SID: 15426566
Canonical SMILES
COc1cc-2c(C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c-2c34)cc1O
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Compound Formula C19H20BrNO4
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
>
Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  2
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
2
Ki = 83000 nM
   TI
   LI
   LO
   TS