Brief Information of the Compound and Protein
Compound Name
2-(4-{[(3-{3-[hydroxy(phenyl)methyl]-8-(trifluoromethyl)quinolin-4-yl}phenyl)amino]methyl}phenyl)acetic acid
    Show/Hide
PubChem ID
CID: 23648469
Canonical SMILES
OC(c1ccccc1)c1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F
    Show/Hide
Compound Formula C32H25F3N2O3
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 812 nM
   TI
   LI
   LO
   TS
2
IC50 = 56.4 nM
   TI
   LI
   LO
   TS