Brief Information of the Compound and Protein
Compound Name
6-amino-4-(4-(dimethylamino)phenyl)-3-p-tolyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
    Show/Hide
PubChem ID
CID: 5067255
Canonical SMILES
Cc1ccc(-c2n[nH]c3c2C(c2ccc(N(C)C)cc2)C(C#N)=C(N)O3)cc1
    Show/Hide
Compound Formula C22H21N5O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000253 CCRF/VCR1000 Homo sapiens (Human)  1
1
EC50 = 3080 nM
   TI
   LI
   LO
   TS