Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-1-(1-(4-fluorophenyl)-2-{4-[4-(2-methoxy-1-naphthyl)butyl]piperazin-1-yl}ethyl)-4-methylpiperazine
    Show/Hide
 PubChem ID
CID: 44396140
Canonical SMILES
COc1ccc2ccccc2c1CCCCN1CCN(CC(N2CCN(C)CC2)c2ccc(F)cc2)CC1
    Show/Hide
Compound Formula C32H43FN4O
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 57.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.9 nM