Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
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 PubChem ID
CID: 135398744
SID: 14883184
Canonical SMILES
CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
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Compound Formula C22H30N6O4S
Compound Structure
Protein Name
 Protein Info 
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 5
>
Phosphodiesterase 5A
Uniprot ID
O54735
Gene Name
PDE5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000070 RFL-6
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
Ki = 1.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3 nM
2 IC50 = 2 nM