Brief Information of the Compound and Protein
Compound Name
3-[[3-(5-Chloro-1H-indol-3-yl)propyl](cyclobutyl)amino]-8-fluorochromane-5-carboxamide
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PubChem ID
CID: 25138912
SID: 56465909
Canonical SMILES
NC(=O)c1ccc(F)c2OCC(Cc12)N(CCCc1c[nH]c2ccc(Cl)cc12)C1CCC1
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Compound Formula C25H27ClFN3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 735 nM
   TI
   LI
   LO
   TS
2
Ki = 3.98 nM
   TI
   LI
   LO
   TS