Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-[[4-(4-amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one
    Show/Hide
 PubChem ID
CID: 10311653
SID: 15319409
Canonical SMILES
Nc1ncnc2nc(-c3ccc(CN4CCC(CC4)n4c5ccccc5[nH]c4=O)cc3)c(cc12)-c1ccccc1
    Show/Hide
Compound Formula C32H29N7O
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1834 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 81 nM