Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-phenyl-7-[4-[[4-(3-pyridin-4-yl-1H-pyrazol-5-yl)piperidin-1-yl]methyl]phenyl]pyrido[2,3-d]pyrimidin-4-amine
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 PubChem ID
CID: 11526695
SID: 16628628
Canonical SMILES
Nc1ncnc2nc(-c3ccc(CN4CCC(CC4)c4cc(n[nH]4)-c4ccncc4)cc3)c(cc12)-c1ccccc1
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Compound Formula C33H30N8
Compound Structure
Protein Name
 Protein Info 
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1198 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 85 nM