Brief Information of the Compound and Protein
Compound Name
1-[1-({4-[5-(5-amino-1,3,4-thiadiazol-2-yl)-3-phenylpyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
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PubChem ID
CID: 11489861
SID: 16591539
Canonical SMILES
Nc1nnc(s1)-c1cnc(-c2ccc(CN3CCC(CC3)n3c4cccnc4[nH]c3=O)cc2)c(c1)-c1ccccc1
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Compound Formula C31H28N8OS
Compound Structure
Protein Name
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A Homo sapiens (Human)  1
1
Activity = 3957 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Activity = 73 nM