Brief Information of the Compound and Protein
Compound Name
2-[4-[2-methyl-8-(2-pyridin-3-ylethynyl)imidazo[4,5-c]quinolin-1-yl]phenyl]acetonitrile
    Show/Hide
PubChem ID
CID: 11350077
SID: 16441710
Canonical SMILES
Cc1nc2cnc3ccc(cc3c2n1-c1ccc(CC#N)cc1)C#Cc1cccnc1
    Show/Hide
Compound Formula C26H17N5
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS