Brief Information of the Compound and Protein
Compound Name
1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE
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PubChem ID
CID: 9886249
SID: 14853646
Canonical SMILES
NC1=NC2(CCN(CC2)C(=O)c2ccc(nc2)C#N)Nc2c(F)ccc(F)c12
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Compound Formula C19H16F2N6O
Compound Structure
Protein Name
Nitric oxide synthase 1
Protein Classification
Enzyme
Uniprot ID
P29475
Gene Name
NOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 840 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 740 nM
2 IC50 = 741.31 nM
3 IC50 = 790 nM
4 IC50 = 1000 nM