Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE
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 PubChem ID
CID: 9886249
SID: 14853646
Canonical SMILES
NC1=NC2(CCN(CC2)C(=O)c2ccc(nc2)C#N)Nc2c(F)ccc(F)c12
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Compound Formula C19H16F2N6O
Compound Structure
Protein Name
 Protein Info 
Nitric oxide synthase, inducible
Protein Classification
Enzyme
Uniprot ID
P35228
Gene Name
NOS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000134 DLD-1
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
2
IC50 = 210 nM
   TI
   LI
   LO
   TS
3
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 35 nM
2 IC50 = 37 nM
3 IC50 = 37.15 nM
4 IC50 = 41 nM
5 IC50 = 900 nM