Brief Information of the Compound and Protein
Compound Name
(2S,6R)-4-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-1,7-dimethyl-10-oxa-4-azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione
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PubChem ID
CID: 44454085
Canonical SMILES
COc1cc(N2C(=O)[C@@H]3[C@H](C2=O)C2(C)CCC3(C)O2)ccc1-c1cnco1
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Compound Formula C20H20N2O5
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
Ki = 12 nM
   TI
   LI
   LO
   TS