Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-((2R,6S)-3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.02,6]dec-4-yl)-2-trifluoromethyl-benzonitrile
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 PubChem ID
CID: 44454157
Canonical SMILES
N#Cc1ccc(N2C(=O)[C@@H]3C4CCC(O4)[C@@H]3C2=O)cc1C(F)(F)F
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Compound Formula C16H11F3N2O3
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 2860 nM
   TI
   LI
   LO
   TS
2
Ki = 1170 nM
   TI
   LI
   LO
   TS