Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide
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 PubChem ID
CID: 60785
SID: 14856245
Canonical SMILES
Fc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
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Compound Formula C23H24FN3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.04 nM
   TI
   LI
   LO
   TS
CL000806 HEK298
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.37 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.04 nM