Brief Information of the Compound and Protein
Compound Name
5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
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PubChem ID
CID: 44389023
Canonical SMILES
COc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1ccc2ccccc2c1
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Compound Formula C24H22N2O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 19 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 4.1 nM
   TI
   LI
   LO
   TS
2
Ki = 19 nM
   TI
   LI
   LO
   TS