Brief Information of the Compound and Protein
Compound Name
4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-phenylamine
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PubChem ID
CID: 44388956
Canonical SMILES
Nc1ccc(cc1)S(=O)(=O)n1cc(C2CCNCC2)c2ccc(Cl)cc12
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Compound Formula C19H20ClN3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 8.5 nM
   TI
   LI
   LO
   TS
2
Ki = 3 nM
   TI
   LI
   LO
   TS