Brief Information of the Compound and Protein
Compound Name
4-(2-(4-bromo-5-(hydroxymethyl)-1H-pyrazol-1-yl)ethylamino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
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PubChem ID
CID: 136036567
Canonical SMILES
Cc1cc(cc2[nH]c(nc12)-c1c(NCCn2ncc(Br)c2CO)cc[nH]c1=O)N1CCOCC1
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Compound Formula C23H26BrN7O3
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000766 SAL1 Homo sapiens (Human)  1
1
IC50 = 796 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 470 nM