Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-ethyl-1-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)piperidin-4-yl]urea
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 PubChem ID
CID: 11526364
SID: 16628304
Canonical SMILES
CCNC(=O)NC1CCN(Cc2ccc(cc2)-c2nc3nc(SC)ncc3cc2-c2ccccc2)CC1
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Compound Formula C29H32N6OS
Compound Structure
Protein Name
 Protein Info 
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5296 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1909 nM