Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-{3-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)piperidin-4-yl]-1H-pyrazol-5-yl}pyridine
    Show/Hide
 PubChem ID
CID: 11621110
SID: 16723993
Canonical SMILES
CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2cc(n[nH]2)-c2ccncc2)cc1
    Show/Hide
Compound Formula C34H31N7S
Compound Structure
Protein Name
 Protein Info 
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 635 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 57 nM