Brief Information of the Compound and Protein
Compound Name
1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)piperidine-4-carboxamide
    Show/Hide
PubChem ID
CID: 11547290
SID: 16649449
Canonical SMILES
CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)C(N)=O)cc1
    Show/Hide
Compound Formula C27H27N5OS
Compound Structure
Protein Name
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A Homo sapiens (Human)  1
1
IC50 = 9259 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 928 nM