Brief Information of the Compound and Protein
Compound Name
7-(4-{[4-(6-fluoro-1H-1,3-benzodiazol-2-yl)piperidin-1-yl]methyl}phenyl)-6-phenylpyrido[2,3-d]pyrimidin-4-amine
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PubChem ID
CID: 11670972
SID: 16774792
Canonical SMILES
Nc1ncnc2nc(-c3ccc(CN4CCC(CC4)c4nc5ccc(F)cc5[nH]4)cc3)c(cc12)-c1ccccc1
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Compound Formula C32H28FN7
Compound Structure
Protein Name
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
AGC protein kinase group
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AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A Homo sapiens (Human)  1
1
IC50 = 1811 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 239 nM