Brief Information of the Compound and Protein
Compound Name
2,2,2-trifluoro-N-((1S,13bR)-6-fluoro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-acetamide
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PubChem ID
CID: 44446558
Canonical SMILES
Fc1ccc2Oc3ccccc3[C@@H]3[C@H](CCCN3c2c1)NC(=O)C(F)(F)F
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Compound Formula C19H16F4N2O2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 198 nM
   TI
   LI
   LO
   TS
2
IC50 = 730 nM
   TI
   LI
   LO
   TS