Brief Information of the Compound and Protein
Compound Name
N-[(6S,7R)-18-chloro-2-azatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaen-6-yl]-2,2,2-trifluoroacetamide
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PubChem ID
CID: 44446556
Canonical SMILES
FC(F)(F)C(=O)N[C@H]1CCCN2[C@@H]1c1ccccc1Cc1ccc(Cl)cc21
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Compound Formula C20H18ClF3N2O
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
   TI
   LI
   LO
   TS