Brief Information of the Compound and Protein
Compound Name
(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(propan-2-yl)-4,5-dihydro-1,3-thiazol-4-one
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PubChem ID
CID: 135513265
SID: 24752298
Canonical SMILES
CC(C)[C@]1(C)SC(N[C@@H](C)c2ccccc2F)=NC1=O
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Compound Formula C15H19FN2OS
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4 nM