Brief Information of the Compound and Protein
Compound Name
2-{[-6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino}-5-(5-methyl-2-oxo-1,3-oxazolidin-3-yl)benzo-1,4-quinone
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PubChem ID
CID: 11683901
SID: 16788088
Canonical SMILES
COCCOc1cc2ncnc(NC3=CC(=O)C(N4CC(C)OC4=O)=CC3=O)c2cc1OC
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Compound Formula C22H22N4O7
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.3 nM
2 IC50 = 10.3 nM
3 IC50 > 1000 nM