Brief Information of the Compound and Protein
Compound Name
3,5-Dimethyl-isoxazole-4-sulfonic acid [3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-amide
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PubChem ID
CID: 11234629
SID: 16318541
Canonical SMILES
Cc1noc(C)c1S(=O)(=O)Nc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1
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Compound Formula C19H24N4O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 0.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1 nM
   TI
   LI
   LO
   TS