Brief Information of the Compound and Protein
Compound Name
 Compound Info 
pyrrolidinylindole, (R)-5b
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 PubChem ID
CID: 11351089
SID: 16442746
Canonical SMILES
CN1CCC[C@@H]1Cc1c[nH]c2ccc(NS(=O)(=O)c3ccc(cc3)C(F)(F)F)cc12
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Compound Formula C21H22F3N3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
2
Ki = 0.4 nM
   TI
   LI
   LO
   TS