Brief Information of the Compound and Protein
Compound Name
(S)-N-(3-((1-methylpyrrolidin-2-yl)methyl)-1H-indol-5-yl)-3-(trifluoromethyl)benzenesulfonamide
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PubChem ID
CID: 11316536
SID: 16405847
Canonical SMILES
CN1CCC[C@H]1Cc1c[nH]c2ccc(NS(=O)(=O)c3cccc(C(F)(F)F)c3)cc12
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Compound Formula C21H22F3N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 14.1 nM
   TI
   LI
   LO
   TS
2
Ki = 12 nM
   TI
   LI
   LO
   TS