Brief Information of the Compound and Protein
Compound Name
1-[(S)-2-Amino-3-(3-methyl-3H-imidazol-4-yl)-propionyl]-5-oxo-pyrrolidine-2-carboxylic acid {2-((S)-2-carbamoyl-pyrrolidin-1-yl)-1-[(S)-1-(1H-imidazol-4-yl)methyl]-2-oxo-ethyl}-amide
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PubChem ID
CID: 44403976
Canonical SMILES
Cn1cncc1C[C@H](N)C(=O)N1[C@@H](CCC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O
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Compound Formula C23H31N9O5
Compound Structure
Protein Name
Thyrotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q01717
Gene Name
TRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001022 HEK293EM Homo sapiens (Human)  2
1
EC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
Ki = 3 nM
   TI
   LI
   LO
   TS