Brief Information of the Compound and Protein
Compound Name
 Compound Info 
((4-Methoxy-phenoxycarbonyl)-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-amino)-acetic acid
    Show/Hide
 PubChem ID
CID: 206044
SID: 14787102
Canonical SMILES
COc1ccc(OC(=O)N(CC(O)=O)Cc2ccc(OCCc3nc(oc3C)-c3ccccc3)cc2)cc1
    Show/Hide
Compound Formula C29H28N2O7
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group C
>
Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
2
EC50 = 1410 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 90 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 35 nM
2 EC50 = 110 nM
3 EC50 = 120 nM
4 IC50 = 120 nM
5 IC50 = 190 nM
6 IC50 = 250 nM