Brief Information of the Compound and Protein
Compound Name
(R)-N2-(4-Chlorobenzyl)-N1-(4-methoxyphenyl)-N2-methylpyrrolidine-1,2-dicarboxamide
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PubChem ID
CID: 25233582
SID: 57585542
Canonical SMILES
COc1ccc(NC(=O)N2CCC[C@@H]2C(=O)N(C)Cc2ccc(Cl)cc2)cc1
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Compound Formula C21H24ClN3O3
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 440 nM
   TI
   LI
   LO
   TS