Brief Information of the Compound and Protein
Compound Name
(1S)-N1-(4-chlorobenzyl)-N1-methyl-N2-(4-(trifluoromethyl)phenyl)cyclopentane-1,2-dicarboxamide
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PubChem ID
CID: 24782826
SID: 49707175
Canonical SMILES
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(cc1)C(F)(F)F
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Compound Formula C21H21ClF3N3O2
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS