Brief Information of the Compound and Protein
Compound Name
N-[5-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2,3-dimethoxyphenyl]quinoline-3-carboxamide
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PubChem ID
CID: 25223105
SID: 57573540
Canonical SMILES
COc1cc2CCN(CCc3ccc(NC(=O)c4cc(NC(=O)c5cnc6ccccc6c5)c(OC)c(OC)c4)cc3)Cc2cc1OC
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Compound Formula C38H38N4O6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000781 MCF7/Topo Homo sapiens (Human)  1
1
IC50 = 858 nM
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