Brief Information of the Compound and Protein
Compound Name
5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline-2,4(1H,3H)-dione
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PubChem ID
CID: 11595209
SID: 16697845
Canonical SMILES
CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(O)cc1
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Compound Formula C16H11Cl2NO3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 12.3 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 615 nM
   TI
   LI
   LO
   TS