Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]naphthalene-2-sulfonamide
    Show/Hide
 PubChem ID
CID: 6918836
SID: 12015927
Canonical SMILES
CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12
    Show/Hide
Compound Formula C22H22ClN3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 0.2 nM
   TI
   LI
   LO
   TS
2
Ki = 0.7 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.2951 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.7 nM