Brief Information of the Compound and Protein
Compound Name
3,6-diethyl-N-((1R,2S)-2-(2-fluoroethoxy)-2,3-dihydro-1H-inden-1-yl)-5-(6-methylpyrimidin-4-yloxy)pyrazin-2-amine
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PubChem ID
CID: 44443654
Canonical SMILES
CCc1nc(Oc2cc(C)ncn2)c(CC)nc1N[C@H]1[C@H](Cc2ccccc12)OCCF
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Compound Formula C24H28FN5O2
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  1
1
Ki = 51 nM
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