Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEBI:46024
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 PubChem ID
CID: 444732
SID: 12013760
Canonical SMILES
C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C
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Compound Formula C17H22N2O3
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 62.9 nM
   TI
   LI
   LO
   TS
3
IC50 = 200 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 4420 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM
2 IC50 = 12 nM
3 IC50 = 12.07 nM
4 IC50 = 12.1 nM
5 IC50 = 29 nM
6 IC50 = 34 nM
7 IC50 = 34.8 nM
8 IC50 = 44 nM
9 IC50 = 85 nM
10 IC50 = 122 nM
11 IC50 = 3800 nM
12 IC50 = 6600 nM
13 IC50 = 7690 nM
14 IC50 = 8439 nM
15 IC50 = 9100 nM
16 Ki = 400 nM
17 Ki = 980 nM
18 Ki = 1400 nM
19 Ki = 14547 nM