Brief Information of the Compound and Protein
Compound Name
(E)-3-(3,5-difluorophenyl)-N-((1S,3R)-3-((4-(4-methoxyphenyl)piperidin-1-yl)methyl)cyclopentyl)acrylamide
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PubChem ID
CID: 25007996
SID: 56349943
Canonical SMILES
COc1ccc(cc1)C1CCN(C[C@@H]2CC[C@@H](C2)NC(=O)\C=C\c2cc(F)cc(F)c2)CC1
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Compound Formula C27H32F2N2O2
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 160 nM
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