Brief Information of the Compound and Protein
Compound Name
(E)-3-(3,5-difluorophenyl)-N-(3-((4-(3,4-difluorophenyl)piperidin-1-yl)methyl)cyclopentyl)acrylamide
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PubChem ID
CID: 44444114
Canonical SMILES
Fc1cc(F)cc(\C=C\C(=O)NC2CCC(CN3CCC(CC3)c3ccc(F)c(F)c3)C2)c1
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Compound Formula C26H28F4N2O
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 790 nM
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