Brief Information of the Compound and Protein
Compound Name
(E)-N-(4-(4-(4-chlorophenyl)piperidin-1-yl)butyl)-3-(3,4,5-trifluorophenyl)acrylamide
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PubChem ID
CID: 44444001
Canonical SMILES
Fc1cc(\C=C\C(=O)NCCCCN2CCC(CC2)c2ccc(Cl)cc2)cc(F)c1F
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Compound Formula C24H26ClF3N2O
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS