Brief Information of the Compound and Protein
Compound Name
(R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)pyridin-3-yl)methanol
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PubChem ID
CID: 11534383
SID: 16636362
Canonical SMILES
C[C@@H]1CN(CCN1c1nc(c([nH]1)-c1ccc(cc1)C(F)(F)F)-c1cc(F)c(F)c(F)c1)c1ncc(CO)cc1Cl
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Compound Formula C27H22ClF6N5O
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O35433
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
IC50 = 4 nM
   TI
   LI
   LO
   TS