Brief Information of the Compound and Protein
Compound Name
2-[1-(Toluene-3-sulfonyl)-1,2,3,6-tetrahydro-pyridin-4-ylethynyl]-pyridine
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PubChem ID
CID: 44403566
Canonical SMILES
Cc1cccc(c1)S(=O)(=O)N1CCC(=CC1)C#Cc1ccccn1
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Compound Formula C19H18N2O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000041 LTK- Mus musculus (Mouse)  1
1
IC50 = 8.2 nM
   TI
   LI
   LO
   TS