Brief Information of the Compound and Protein
Compound Name
2-[3-(2-pyridin-2-ylethynyl)cyclohex-2-en-1-yl]isoindole-1,3-dione
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PubChem ID
CID: 71459940
Canonical SMILES
O=C1N(C2CCCC(=C2)C#Cc2ccccn2)C(=O)c2ccccc12
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Compound Formula C21H16N2O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000041 LTK- Mus musculus (Mouse)  1
1
IC50 = 27 nM
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