Brief Information of the Compound and Protein
Compound Name
2-(1-Phenylmethanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-ylethynyl)-pyridine
    Show/Hide
PubChem ID
CID: 44403561
Canonical SMILES
O=S(=O)(Cc1ccccc1)N1CCC(=CC1)C#Cc1ccccn1
    Show/Hide
Compound Formula C19H18N2O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000041 LTK- Mus musculus (Mouse)  1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS