Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-methyl-4-[3-(2-oxoimidazolidin-1-yl)pyrazol-1-yl]-2,3-dihydropyrrolo[2,3-b]pyridin-1-yl]-3-(trifluoromethoxy)benzonitrile
    Show/Hide
 PubChem ID
CID: 11282792
SID: 16369731
Canonical SMILES
Cc1cc(c2CCN(c2n1)c1ccc(cc1OC(F)(F)F)C#N)-n1ccc(n1)N1CCNC1=O
    Show/Hide
Compound Formula C22H18F3N7O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 120.23 nM
   TI
   LI
   LO
   TS