Brief Information of the Compound and Protein
Compound Name
1-[1-[6-methyl-1-[2-methyl-4-(trifluoromethoxy)phenyl]-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]imidazolidin-2-one
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PubChem ID
CID: 11317069
SID: 16406385
Canonical SMILES
Cc1cc(c2CCN(c2n1)c1ccc(OC(F)(F)F)cc1C)-n1ccc(n1)N1CCNC1=O
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Compound Formula C22H21F3N6O2
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 67.61 nM
   TI
   LI
   LO
   TS