Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-[1-(2,4-dichlorophenyl)-6-methyl-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]-1H-imidazol-2-one
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 PubChem ID
CID: 44589317
Canonical SMILES
Cc1cc(c2CCN(c2n1)c1ccc(Cl)cc1Cl)-n1ccc(n1)-n1cc[nH]c1=O
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Compound Formula C20H16Cl2N6O
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS